Cardiotoxicity is the occurrence of heart electrophysiology dysfunction or muscle damage. The heart becomes weaker and is not as efficient in pumping and therefore circulating blood. Cardiotoxicity may be caused by chemotherapy (an usual example is the class of anthracyclines) treatment, complications from anorexia nervosa, adverse effects of heavy metals intake, or an incorrectly administered drug such as bupivacaine.One of the ways to detect cardiotoxicity at early stages when there is a subconical ...

cardiotoxicity

The-Most-Dangerous-Food-Enhancers-in-Our-Diet

The Most Dangerous Food Enhancers in Our Diet 

The-Most-Dangerous-Food-Enhancers-in-Our-Diet_0_0

Calcium-sulphite-E226

Calcium sulphite E226  

Calcium-sulphite-E226_0_0

Very widely used, mainly as a preservative or antioxidant in a wide range of foods - from burgers to biscuits, dried fruits and vegetables and other foods. In the U.S., for example, sulfites are banned in many foods, including meat, because they make old products look fresh. They can cause bronchial problems, redness, low blood pressure, numbness and anaphylactic shock.&nbsp;

Calcium-sulphite-E226_0_1

The International Labour Organization recommends avoiding it if you suffer from bronchial asthma, cardiovascular or respiratory problems, and emphysema. The European Food and Regulatory Agency (EFSA) also said there were some concerns about the consumption of sulphites, but there was insufficient information to confirm its harmful effects in humans. The scientists point out that the available toxicity data are not sufficient to derive an acceptable daily intake (ADI) level. Instead, they calculate exposure limits (MOEs) by considering dietary intake and dose associated with neurotoxic effects in animal tests. 1

Monosodium-glutamate-(MSG)-E621

Monosodium glutamate (MSG) E621

Monosodium-glutamate-(MSG)-E621_0_0

Widely used as flavoring and flavoring. In a number of people, its consumption can lead to unpleasant symptoms, including tension in the head, seizures, chest pain, headache, nausea, burning sensation and tightness of the face. Many baby food manufacturers have stopped adding this substance to their foods. Some of the reasons lie in the next paragraph.

Monosodium-glutamate-(MSG)-E621_0_1

Preclinical studies have linked administration of monosodium glutamate to cardiotoxicity, hepatotoxicity, neurotoxicity, low-grade inflammation, metabolic disorder and premature malignancies, along with changes in behaviour. In addition, relationships between MSG consumption and tumorigenesis, increased oxidative stress and apoptosis in thymocytes, as well as genotoxic effects in lymphocytes have been reported. &nbsp;<a href="https://pubmed.ncbi.nlm.nih.gov/31920467/" target="_blank" data-ref="A review of the alleged health hazards of monosodium glutamate - PubMed" rel="noopener">[Ref. 1]</a>&nbsp; Although other scientists later found methodological errors and did not confirm the same effects in humans, the potential harmful action remained a risk. In any case, they occur with long-term increased consumption of monosodium glutamate.&nbsp;

Ponceau-4R-E124

Ponceau 4R E124  

Ponceau-4R-E124_0_0

Ponceau is widely used as a colorant in foods. People who suffer from asthma, rhinitis, urticaria, may find that their symptoms worsen after eating foods containing this colorant.

Ponceau-4R-E124_0_1

Potassium-benzoate-E212

Potassium benzoate E212

Potassium-benzoate-E212_0_0

Preservative in many foods, including beverages, low-sugar products, cereals, meat products. Potassium benzoate may temporarily inhibit the function of digestive enzymes and may reduce glycine and amino acid levels. It should be avoided by people with allergic conditions such as hay fever, hives, and asthma. 3

Potassium-nitrite-E249

Potassium nitrite E249  

Potassium-nitrite-E249_0_0

It is used as a preservative in canned meat and others. It may contribute to three main health problems: it can reduce the oxygen-carrying capacity of the blood; It can be combined with other substances to form nitrosamines, which are carcinogenic, and can have a negative effect on the adrenal glands.

Propyl-P-hydroxybenzoate,-propylparaben-E216

Propyl P-hydroxybenzoate, propylparaben E216 

Propyl-P-hydroxybenzoate,-propylparaben-E216_0_0

E216 is a preservative in patetes, cereals, snacks, meat products and confectionery. Parabens have been identified as the cause of chronic dermatitis in many cases.

Propyl-P-hydroxybenzoate,-propylparaben-E216_0_1

Sodium-metabisulphite-E223

Sodium metabisulphite E223  

Sodium-metabisulphite-E223_0_0

E223 is widely used as a preservative and antioxidant. It can provoke life-threatening asthma - there is a documented case of severe asthma after eating a salad with vinegar-based dressing containing E223. For this preservative, there is evidence that it causes bowel disorder, skin disorders and destroys vitamin B12 - one of the most important B vitamins. IV

Sodium-sulphite-E221

Sodium sulphite E221 

Sodium-sulphite-E221_0_0

Preservative used in the production of wine, other food and beverages. Sulfites have been associated with triggering asthma attacks.

Stannous-chloride-E512

Stannous chloride E512 

Stannous-chloride-E512_0_0

Antioxidant and color-preserving agent in canned and bottled foods, also in fruit juices. There is evidence of acute poisoning when ingesting fruit juices with concentrations above 250 mg. per liter. Poisoning causes sumptoms such as nausea, vomiting, diarrhea and headache.

Stannous-chloride-E512_0_1

Sulphur-dioxide-E220

Sulphur dioxide E220  

Sulphur-dioxide-E220_0_0

Very widely used preservative in food and drink. Sulfur dioxide reacts with a wide range of substances found in food, including various essential vitamins, minerals, enzymes, and essential fatty acids. Most often they cause problems in the bronchi, especially in people who are prone to asthma. Other side effects may include hypotension (low blood pressure), redness, numbness and anaphylactic shock. According to the International Labour Organization, you should avoid E220 if you suffer from conjunctivitis, bronchitis,&nbsp; emphysema, bronchial asthma or cardiovascular disease.&nbsp;

Sunset-Yellow-E110

Sunset Yellow E110  

Sunset-Yellow-E110_0_0

Widely used colorant in food. Some animal studies have shown growth retardation and severe weight loss. People with asthma, rhinitis or urticaria should avoid this colorant and the products that contain it.

Tartrazine-E102

Tartrazine E102 

Tartrazine-E102_0_0

A widely used food coloring agent that can cause allergic reactions in about 15 percent of the population. It can be the cause of asthma attacks and is implicated in attacks of hyperactivity disorder in children. People who suffer from asthma, rhinitis, urticaria, may find that symptoms worsen after consumption.

Tartrazine-E102_0_1

For tartrazine, oral administration has been shown to accelerate the incidence and development of 7,12-dimethylbenz(a)-induced anthracene (DMBA) breast cancer in rats. 5

Tartrazine-E102_0_2

Tartrazine has also been documented for its effect on hyperactivity in children, as have E104 (quinoline yellow) and E110 (sunset yellow FCF). 6

Banned-food-enhancers-in-Europe

Banned food enhancers in Europe 

Banned-food-enhancers-in-Europe_1_0

The latest data shows that the European Commission is banning titanium dioxide (E171) as a food enhancer in the European Union (EU) as of 7 February 2022.&nbsp;

Banned-food-enhancers-in-Europe_1_1

<ul><li style="font-weight: 400;" aria-level="1">Potassium bromate E294&nbsp;</li><li style="font-weight: 400;" aria-level="1">Azodicarbonamide E927</li><li style="font-weight: 400;" aria-level="1">Brominated vegetable oil (BVO) E443</li><li style="font-weight: 400;" aria-level="1">Olestra</li><li style="font-weight: 400;" aria-level="1">Rhodamine B</li><li style="font-weight: 400;" aria-level="1">Propylparaben E216</li><li style="font-weight: 400;" aria-level="1">Artificial colors (yellow No 5, No 6, red No 40)</li></ul>Only food enhancers that are listed in EU legislation can be added to food and this can only be done under certain conditions. Enhancers authorised in food and their conditions of use can be found in Annex II to Regulation (EC) No 1333/2008 on nutritional enhancers. 7

Many of our favorite foods and drinks, such as carbonated drinks, cream powder, instant soups, chips, sweets, salad dressing, soy sauce and more, contain dangerous food enhancers. For some of them there is evidence of the negative effects on health in humans and animals, while others have been considered only in animals. More disturbing is that some of these dietary enhancers have been linked to the development of cancers as well as hyperactivity in children. In many countries, these food enhancers are banned, e.g. E151 is banned in Australia, Austria, America, Germany, Norway, Sweden, Switzerland, Belgium and France; E133 is banned in Austria, Sweden, Switzerland, France, Germany and Norway, etc. We have also made a list of food enhancers banned in Europe so that you know and check that the products you buy do not contain them and do not endanger your health.&nbsp;&nbsp;

The Most Dangerous Nutritional Enhancers in Our Diet (Part 2)

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Бетина Цветкова

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Author: Rositsa Tashkova, Master of Molecular Biology and Microbiology

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Cancer is extremely prevalent and is one of the leading causes of death in the world. The most common treatments are chemotherapy and radiation therapy. But unfortunately, they have many and severe side effects that worsen, albeit temporarily, the quality of life of patients and are a major reason for refusing treatment.

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Fortunately, some natural products can alleviate the side effects induced by chemotherapy and radiation therapy:

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<ul>
<li style="font-weight: 400;" aria-level="1">oral mucositis (inflammation and mouth ulcers),</li>
<li style="font-weight: 400;" aria-level="1">gastrointestinal toxicity (nausea, vomiting),</li>
<li style="font-weight: 400;" aria-level="1">hepatotoxicity (liver),</li>
<li style="font-weight: 400;" aria-level="1">nephrotoxicity (kidneys),</li>
<li style="font-weight: 400;" aria-level="1">damage to the hematopoietic system (blood formation),</li>
<li style="font-weight: 400;" aria-level="1">cardiotoxicity (heart),</li>
<li style="font-weight: 400;" aria-level="1">neurotoxicity (nervous system).</li>
</ul>

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In this article, you will find information on the topic based on research. We hope it will be useful for you or your relatives and acquaintances suffering from oncological disease.

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Mechanisms-behind-herbs-ability-to-suppress-side-effects

Mechanisms behind herbs ability to suppress side effects

Mechanisms-behind-herbs-ability-to-suppress-side-effects_0_0

Natural products, including raw extracts enriched with bioactive components and pure compounds derived from herbs, as well as herbal formulas, can effectively reduce the strength of chemotherapy and radiation therapy induced side effects mainly due to their antioxidant and anti-inflammatory actions.

Mechanisms-behind-herbs-ability-to-suppress-side-effects_0_1

In addition, certain natural products are able to [<a href="https://www.bioseek.eu/en/eng/research/pubmed/Natural_Product_Interventions_for_Chemotherapy_and_Radiotherapy_Induced_Side_Effects_30459615#B109" target="_blank" rel="noopener">ref.1</a>]:

Mechanisms-behind-herbs-ability-to-suppress-side-effects_0_2

<ul>
<li style="font-weight: 400;" aria-level="1">suppress the oral mucositis induced by chemotherapy and radiation therapy by not allowing the occurrence of an infection,</li>
<li style="font-weight: 400;" aria-level="1">mitigate gastrointestinal toxicity by regulating the intestinal microflora,</li>
<li style="font-weight: 400;" aria-level="1">limit liver damage by protecting mitochondria,</li>
<li style="font-weight: 400;" aria-level="1">suppress kidney damage by modulating immunity,</li>
<li style="font-weight: 400;" aria-level="1">reduce damage to the blood-creating process by improving the hematopoietic microenvironment,</li>
<li style="font-weight: 400;" aria-level="1">reduce cardiotoxicity by balancing energy metabolism,</li>
<li style="font-weight: 400;" aria-level="1">prevent neurotoxicity by protecting the nervous system.</li>
</ul>

Mechanisms-behind-herbs-ability-to-suppress-side-effects_0_3

Herbs-against-oral-mucositis

Herbs against oral mucositis

Herbs-against-oral-mucositis_1_0

Oral mucositis is a common negative side effect of chemo and radiation therapy, especially at larger doses or in the treatment of cancerous formations in the head area. It is characterized by edema, soreness and the appearance of ulcers in the mouth, and can alter the course of treatment if it worsens.

Herbs-against-oral-mucositis_1_1

It is due to oxidative stress and inflammation caused by theset herapies.

Herbs-against-oral-mucositis_1_2

Medicinal plants, which are evidenced to help with oral mucositis, are:

Herbs-against-oral-mucositis_1_3

<ul>
<li>Broadleaf plantain (Plantago major) - is effective in the treatment of wounds as it has anti-inflammatory, antibacterial, antiviral and antioxidant properties. A randomised triple-blind phase III clinical trial shows that broad-field plantain extract, in combination with sodium bicarbonate (baking soda) solution 5%, can effectively control oral mucositis in cancer patients [<a href="https://www.ejoncologynursing.com/article/S1462-3889(17)30258-2/fulltext" target="_blank" rel="noopener">ref.2</a>].</li>
</ul>

Herbs-against-oral-mucositis_1_4

Herbs-against-oral-mucositis_1_5

<ul>
<li>Chamomile (Matricaria chamomilla) - according to some studies, chamomile extract, used as mouthwash, slows down the appearance of oral mucositis and reduces its strength if it appears. [<a href="https://www.hindawi.com/journals/tswj/2018/4392184/" target="_blank" rel="noopener">ref.3</a>]</li>
<li>Aloe vera - according to some studies, the intake of aloe vera juice or rinsing the mouth with 5 ml of aloe vera solution for two minutes, three times a day, for 14 days [<a href="https://www.bioseek.eu/en/eng/research/pubmed/The_Effect_of_Aloe_Vera_Solution_on_Chemotherapy_Induced_Stomatitis_in_Clients_with_Lymphoma_and_Leukemia_A_Randomized_Controlled_Clinical_Trial_27218109" target="_blank" rel="noopener">ref.5</a>] improves the condition of sufferers of oral mucositis as a result of chemo- or radiation therapy.</li>
<li aria-level="1">Marigold (Calendula officinalis) - there is evidence that calendula extract can prevent or relieve oral mucositis. Probably this is due to the content of the strong antioxidant quercetin in this herb. [<a href="https://www.bioseek.eu/en/eng/research/pubmed/Antioxidant_capacity_of_calendula_officinalis_flowers_extract_and_prevention_of_radiation_induced_oropharyngeal_mucositis_in_patients_with_head_and_neck_cancers_a_randomized_controlled_clinical_study_23497687" target="_blank" rel="noopener">ref.4</a>]</li>
</ul>

Herbs-against-oral-mucositis_1_6

Herbs-against-oral-mucositis_1_7

<ul>
<li style="font-weight: 400;" aria-level="1">Other natural remedies reported to have given positive results are: turmeric (not to be taken in treatment with paclitaxel, since the combination can damage the liver), ginger, mulberry molasses, honey and propolis, but the latter should not be used in severe cases of oral mucositis. [<a href="https://www.bioseek.eu/en/eng/research/pubmed/Natural_Product_Interventions_for_Chemotherapy_and_Radiotherapy_Induced_Side_Effects_30459615#B109" target="_blank" rel="noopener">ref.1</a>]</li>
</ul>

Herbs-against-gastrointestinal-toxicity

Herbs against gastrointestinal toxicity

Herbs-against-gastrointestinal-toxicity_2_0

The most common manifestations of gastrointestinal toxicity caused by chemotherapy and radiation therapy are nausea, vomiting and diarrhea. One of the causes is the disruption of the balance in the intestinal flora or so-called dysbiosis. There is a deterioration in digestion and absorption of nutrients, as well as inflammation of the esophagus (esophagitis) and intestines (enteropathy).

Herbs-against-gastrointestinal-toxicity_2_1

There are many studies that have checked the effects of various medicinal plants against the gastrointestinal toxicity of chemo- and radiation therapy. Here we will look at those who have shown effectiveness in humans:

Herbs-against-gastrointestinal-toxicity_2_2

<ul>
<li style="font-weight: 400;" aria-level="1">Ginger (Zingiber officinale) - has been found to suppress nausea and vomiting and restore appetite in cancer patients;</li>
<li style="font-weight: 400;" aria-level="1">Ginseng (Panax ginseng) - according to a randomized double-blind placebo-controlled study from 2017, ginseng reduces the symptoms of nausea, vomiting, shortness of breath and fatigue, and its efficacy and safety can improve the quality of life of patients [<a href="https://www.mdpi.com/2072-6643/9/7/772" target="_blank" rel="noopener">ref.7</a>];</li>
</ul>

Herbs-against-gastrointestinal-toxicity_2_3

Herbs-against-gastrointestinal-toxicity_2_4

<ul>
<li style="font-weight: 400;" aria-level="1">Aloe vera - it has anti-inflammatory effect;</li>
<li style="font-weight: 400;" aria-level="1">Green tea (Camellia sinensis) - has a good effect due to the antioxidant, antibacterial and anti-inflammatory properties of catechins in it, as well as its property to suppress intestinal motility.</li>
</ul>

Herbs-against-hepatotoxicity-(liver-toxicity)

Herbs against hepatotoxicity (liver toxicity)

Herbs-against-hepatotoxicity-(liver-toxicity)_3_0

Liver damage can occur both under the influence of chemotherapy and with improper use of herbs. Therefore, it is important to keep in mind that plants are not necessarily harmless and control by a specialist is an important part of the herbal treatment.

Herbs-against-hepatotoxicity-(liver-toxicity)_3_1

There are several herbs that have shown a positive effect against the toxic effects of chemo- and radiation therapy on the liver:

Herbs-against-hepatotoxicity-(liver-toxicity)_3_2

<ul>
<li style="font-weight: 400;" aria-level="1">Milk thistle (Silybum marianum) - the effect is due to the antioxidant and anti-inflammatory properties of the plant, as well as its ability to suppress fibrosis;</li>
</ul>

Herbs-against-hepatotoxicity-(liver-toxicity)_3_3

Herbs-against-hepatotoxicity-(liver-toxicity)_3_4

<ul>
<li style="font-weight: 400;" aria-level="1">Shiitake (Lentinula edodes) - the extract of the mycelium of the shiitake fungus contains an active hemicellulose component (AHCC), which can reduce hematotoxicity and hepatotoxicity and improve the quality of life of patients with advanced cancer during chemotherapy [<a href="https://www.tandfonline.com/doi/abs/10.1080/01635581.2014.884232" target="_blank" rel="noopener">ref.8</a>]. </li>
</ul>

Herbs-against-nephrotoxicity-(kidneys)

Herbs against nephrotoxicity (kidneys)

Herbs-against-nephrotoxicity-(kidneys)_4_0

Nephrotoxicity is one of the most serious side effects of treatment with the chemotherapeutic cisplatin , and the kidneys are very sensitive to radiation.&nbsp;

Herbs-against-nephrotoxicity-(kidneys)_4_1

In studies involving cancer patients, a positive effect was observed with honey, royal jelly and the substance lycopene, which is found in tomatoes, grapefruit and watermelon.

Herbs-against-nephrotoxicity-(kidneys)_4_2

In experimental animals, the alcoholic extract of marjoram (Origanum majorana, in cisplatin treatment), sweet flag (Acorus calamus), quercetin, grape seed extract, ginger extract, also showed a good effect.&nbsp;[<a href="https://www.bioseek.eu/en/eng/research/pubmed/Natural_Product_Interventions_for_Chemotherapy_and_Radiotherapy_Induced_Side_Effects_30459615#B109" target="_blank" rel="noopener">ref.1</a>]

Herbs-against-nephrotoxicity-(kidneys)_4_3

Herbs-supporting-the-hematopoietic-system-(blood-formation)

Herbs supporting the hematopoietic system (blood formation)

Herbs-supporting-the-hematopoietic-system-(blood-formation)_5_0

Myelosuppression with leukocytopenia, erythrocytopenia and thrombocytopenia are serious and frequent side effects during cancer treatment. In patients with myelosuppression due to chemotherapy and radiotherapy, infections and inflammations are often observed.

Herbs-supporting-the-hematopoietic-system-(blood-formation)_5_1

Antioxidant natural products can lower the amount of free radicals produced as a result of chemotherapy and radiation therapy, preventing them from killing white blood cells and bone marrow suppression.

Herbs-supporting-the-hematopoietic-system-(blood-formation)_5_2

In humans, positive effects have been found with the use of ginseng, as well as some herbal formulas from Traditional Chinese medicine (TCM):

Herbs-supporting-the-hematopoietic-system-(blood-formation)_5_3

<ul>
<li style="font-weight: 400;" aria-level="1">Shuanghuang Shengbai - in the form of granules, contains astragalus (Astragalus membranaceus), Rhizoma polygonati (root of a plant of the genus Polygonatum), Rhizoma drynariae (fern root of the species Drynaria roosii), Fructus ligustri (fruits of Ligustrum lucidum), Radix trichosanthis (root of a plant of the genus Trichosanthes) and Herba epimedii [<a href="https://www.bioseek.eu/en/eng/research/pubmed/Shuanghuang_Shengbai_granule_cures_myelosuppression_and_suppresses_lung_cancer_progression_mechanism_and_therapeutic_targets_from_the_aspect_of_microRNAs_28977934" target="_blank" rel="noopener">ref.9</a>];</li>
<li style="font-weight: 400;" aria-level="1">Danggui Buxue - decoction, which contains roots of astragalus and dong quai or female ginseng (Radix astragali and Radix Angelicae sinensis).</li>
</ul>

Herbs-supporting-the-hematopoietic-system-(blood-formation)_5_4

Herbs-against-cardiotoxicity-(heart)

Herbs against cardiotoxicity (heart)

Herbs-against-cardiotoxicity-(heart)_6_0

The imbalance of energy metabolism and oxidative stress leads to cardiotoxicity induced by chemotherapeutic agents, and cardiac damage from radiation therapy is a major problem for those struggling with cancer.

Herbs-against-cardiotoxicity-(heart)_6_1

The following herbs might be hepful: parsley oil, black grape juice, flaxseed oil, green tea and Chinese herbal formula Sheng-Mai-San, which contains: ginseng root, monkey grass (Liriope spicata) and Chinese magnolia-vine fruits (Schisandra chinensis).

Herbs-against-neurotoxicity-(nervous-system)

Herbs against neurotoxicity (nervous system)

Herbs-against-neurotoxicity-(nervous-system)_7_0

Neurotoxicity is a common adverse effect of chemotherapy and radiation therapy of cancer and causes excruciating pain to patients. These therapies lead to peripheral neuropathy.

Herbs-against-neurotoxicity-(nervous-system)_7_1

Helpful herbs are: St. John's wort (Hypericum perforatum), green tea, grape seed oil, turmeric, astragalus root.

Herbs-against-neurotoxicity-(nervous-system)_7_2

Before taking these herbs, please discuss it with your health care provider due to the specifics of the treatment of each individual patient. Some herbs interact adversely&nbsp;with specific medicines and whether they are suitable can only be judged by a specialist.

Q&amp;A

Q&amp;A_8_0

What are the possible side effects of chemotherapy?

Q&amp;A_8_1

Fatigue is one of the most common side effects of chemotherapy. Other side effects can be:

Q&amp;A_8_2

<ul>
<li>Feeling sick,</li>
<li>Hair loss,</li>
<li>Infections,</li>
<li>Anemia,</li>
<li>Bruises and easy bleeding,</li>
<li>Inflammation of the mouth, sores, mucosal ulcers,</li>
<li>Loss of appetite,</li>
<li>Dry, itchy, red skin,</li>
<li>Brittle nails,</li>
<li>Insomnia,</li>
<li>Problems with memory and concentration,</li>
<li>Diarrhea and constipation,</li>
<li>Impaired libido and infertility,</li>
<li>Emotional problems, stress, anxiety.</li>
</ul>

Q&amp;A_8_3

What are the recommendations after chemotherapy?

Q&amp;A_8_4

It is advisable to better your mouth hygiene, as chemotherapy can lead to unpleasant sores in the mouth: brushing your teeth 2-3 times a day, for 2-3 minutes, with fluoride toothpaste and a soft toothbrush. Do not use mouthwash that contains alcohol. It is good to rinse your mouth with a solution of soda and table salt 4 times a day (2.5 g of soda + 2.5 g of salt in 240 ml of water).

Q&amp;A_8_5

Avoid sugar, including in chewing gum and candy. Special attention should be paid to food and its safety to avoid infections.

Q&amp;A_8_6

Avoid crowds, do not receive sick guests (cold, flu, coronavirus) at home, wash hands very often, avoid contact with soil, cats and animals that have not been vaccinated, do not smoke, be careful with exposure in the sun, maintain physical activity through walks.

Q&amp;A_8_7

Are there forbidden foods after chemotherapy?

Q&amp;A_8_8

Due to the increased risk of infection after chemotherapy, it is important not to consume uncooked or spoiled foods, raw or semi-raw meats, fish and eggs, unpasteurized cheeses and milk, raw vegetables that are difficult to wash well (eg lettuce and other leafy vegetables).

Q&amp;A_8_9

Avoid sugar, sugary and sweetened foods and beverages.

Q&amp;A_8_10

Avoid red meat, white flour, trans fats, alcohol.

cardiotoxicity

Herbs that relieve chemotherapy and radiation therapy adverse side effects