Hyperplasia (from ancient Greek ὑπέρ huper, 'over' + πλάσις plasis, 'formation'), or hypergenesis, is an increase in the amount of organic tissue that results from cell proliferation. It may lead to the gross enlargement of an organ, and the term is sometimes confused with benign neoplasia or benign tumor.Hyperplasia is a common preneoplastic response to stimulus. Microscopically, cells resemble normal cells but are increased in numbers. Sometimes cells may also be increased in size (hypertrophy). ...

hyperplasia

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Unmasking-the-Nutritional-Profile-of-Pumpkin-Seeds

Unmasking the Nutritional Profile of Pumpkin Seeds

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Pumpkin seeds, or pepitas, are a trove of nutrients. They're packed with antioxidants, iron, zinc, and magnesium - all of which contribute to various aspects of your health. But their true power shines when we look at their high concentration of phytosterols, compounds known to support prostate health.

The-Prostate-Promoting-Power-of-Pumpkin-Seeds

 The Prostate-Promoting Power of Pumpkin Seeds

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Pumpkin seeds are specifically known for promoting prostate health due to the presence of phytosterols. These plant-based compounds may help shrink the prostate and alleviate symptoms related to benign prostatic hyperplasia (BPH), a condition often seen in older men. Moreover, the high zinc content in pumpkin seeds plays a critical role in maintaining prostate health.

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Addressing Prostate Health Issues with Pumpkin Seeds

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Including pumpkin seeds in your diet can be a simple and effective way to ensure a healthy prostate. Regular consumption of these seeds can provide relief from BPH symptoms such as frequent urination. Research also suggests that pumpkin seed oil can inhibit testosterone-induced hyperplasia of the prostate, further cementing their role in prostate health.

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How-to-Incorporate-Pumpkin-Seeds-into-Your-Diet

How to Incorporate Pumpkin Seeds into Your Diet

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Adding pumpkin seeds to your diet is straightforward. You can eat them raw, roasted, or in the form of pumpkin seed oil. They can be added to salads, granola, yogurts, or even consumed as a snack on their own. This versatile seed can be incorporated into various meals throughout the day, making it an effortless addition to your diet.

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Pumpkin Seeds and Their Anticancer Potential

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Emerging studies suggest that the nutritional profile of pumpkin seeds may have anticancer properties, specifically in relation to prostate cancer. The high concentration of antioxidants in pumpkin seeds can help fight off harmful free radicals, which are often linked to the development of various types of cancer.

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The phytosterols present in pumpkin seeds not only support prostate health but also show promise in slowing down the growth of cancer cells. An additional compound, known as delta-7 sterine, has also demonstrated potential in blocking the proliferation of prostate cancer cells.

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Other Natural Foods Beneficial for Prostate Health

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While pumpkin seeds hold a significant place in promoting prostate health, other natural foods exhibit similar effects. Tomatoes, broccoli, green tea, pomegranates, and turmeric all have unique properties that contribute to a healthier prostate and potentially reduce the risk of prostate cancer.

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Easy-and-Delicious-Recipes-with-Pumpkin-Seeds

 Easy and Delicious Recipes with Pumpkin Seeds

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Boosting your prostate health can be as simple and enjoyable as incorporating pumpkin seeds into your meals. Here are a few delightful recipes that bring out the best of pumpkin seeds:

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Pumpkin Seed Pesto

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Add a twist to your traditional pesto by using pumpkin seeds. Blend 1 cup of pumpkin seeds with fresh basil, a couple of garlic cloves, parmesan cheese, olive oil, and lemon juice until smooth. This pesto can be used as a pasta sauce, sandwich spread, or a dip for your favorite veggies.

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Roasted Pumpkin Seeds

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Don&rsquo;t discard the seeds when you scoop out a pumpkin. Rinse them, toss with a bit of olive oil, sprinkle with sea salt, and roast at 180&deg;C until crispy and golden brown. A delicious and healthy snack, ready in no time.

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Pumpkin Seed and Oat Granola

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Make your own granola by combining 2 cups of oats, 1 cup of pumpkin seeds, a drizzle of honey, and a pinch of salt. Bake until golden and let it cool. This granola is perfect for a nutritious breakfast, served with yogurt and fresh fruit.

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Pumpkin Seed Smoothie

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For a quick nutrient boost, add a handful of pumpkin seeds to your morning smoothie. Try blending them with a banana, spinach, almond milk, and a touch of honey for a healthy, delicious start to your day.

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Quinoa Salad with Pumpkin Seeds

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Add crunch and nutrition to your salad by tossing in roasted pumpkin seeds. A salad made with quinoa, fresh vegetables, feta cheese, and a handful of pumpkin seeds will not only be tasty but will also keep you satiated for longer.

Pumpkin seeds are more than just a tasty snack - they're a nutrient-rich food with the potential to significantly improve prostate health. Regular consumption of these small, yet mighty seeds may aid in reducing BPH symptoms and promoting overall prostate health. With their anticancer potential and their easy incorporation into meals, embracing the benefits of pumpkin seeds today can contribute to a healthier tomorrow.

 Powerhouse of Health: The Unbeatable Benefits of Pumpkin Seeds for Prostate Health

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 Powerhouse of Health: The Unbeatable Benefits of Pumpkin Seeds for Pr

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What-is-collagen?

What is collagen? 

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Collagen is a member of the family of naturally occurring proteins. It is one of the most abundant proteins present in mammals and is responsible for performing various important biological functions.&nbsp;

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Collagen is the basic building structure of connective tissue in the human body. It is an essential structural protein, forming molecular "cables" that strengthen tendons and elastic sheets that support the skin and internal organs. Bones and teeth are built by adding mineral crystals to collagen. Collagen provides structure to our bodies by protecting and maintaining softer tissues and connecting them to the skeleton. But despite its critical function in the body, collagen is a relatively simple protein. <a href="https://www.ncbi.nlm.nih.gov/books/NBK507709/" target="_blank" data-ref="Page not available - NCBI BookshelfTwitterFacebookLinkedInGitHubNCBI Insights BlogTwitterFacebookYoutube" rel="noopener">[ref.</a>&nbsp;1]&nbsp;

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About a quarter of all proteins in your body are in the form of collagen. Each fiber of collagen contains thousands of individual collagen molecules that are bonded together by cross-linking and staggered covalent bonds. Covalent bonds are the strongest bonds that can exist between protein molecules. The collagen molecules themselves are made up of 3 separate polypeptides or strings of amino acids. The filaments wrap around each other in an alpha-helix. The spiral is formed due to the correct amino acid sequence of the strands. The sequence is a recurrent pattern of glycine-proline-hydroxyproline, and there may be another amino acid according to the type of collagen (for example, alanine, arginine and others).&nbsp;

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There are over 20 known types of collagen, but four of them are the most common:

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<ul><li style="font-weight: 400;" aria-level="1">Type I: the most common type found in all connective tissues in the body;</li><li style="font-weight: 400;" aria-level="1">Type ll: located in the joints and intervertebral discs (pillows that serve as shock absorbers on the spine);</li><li style="font-weight: 400;" aria-level="1">Type III: the main component of reticular fibers, which are found in the skin and blood vessels;</li><li style="font-weight: 400;" aria-level="1">Type IV: a component of the kidneys, inner ear and eye lenses.</li></ul>The unique properties of each type of collagen are due to segments in collagen molecules that disrupt the spiral structure. They are caused by the amino acids in the X positions of the polypeptide sequence. Different tissues of the body contain different amounts of each type of collagen. For example, cartilage contains a lot of type II collagen, while type IV collagen&nbsp; is mostly found in basal membranes. &nbsp;<a href="https://www.jomfp.in/article.asp?issn=0973-029X;year=2016;volume=20;issue=2;spage=276;epage=283;aulast=Deshmukh" target="_blank" data-ref="Enigmatic insight into collagen Deshmukh SN, Dive AM, Moharil R, Munde P - J Oral Maxillofac Pathol" rel="noopener">[ref. 2]</a>&nbsp;

Collagen-in-the-form-of-collagen-peptides

Collagen in the form of collagen peptides 

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For many years, collagen supplements were in the form of topical creams containing collagen, or collagen powder, to provide the missing amounts of collagen and exert a potential anti-aging effect.

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But given the size of collagen — as simple as a structure, but quite a large molecule — experts were looking for a way to perfect these products and found it. As they found, something so large is not optimally absorbed into the skin or can not pass deep into the layers of the skin, where it is necessary to realize its effect.

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A new generation of collagen products overcome this problem by being available in the form of hydrolyzed collagen and collagen peptides – much smaller strings of amino acids that make up collagen. These shorter chains are more easily absorbed by the human body and can be made into powder or packaged in pills to be taken orally.&nbsp;

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Through the process of hydrolysis, one of the main advantages of collagen peptides is provided. Because collagen molecules have been broken down, a supplement of this type is easier to digest and absorb by the body. And this is really important, because when taking collagen in its entire form, the molecules are too large to pass through the gastric mucosa. This means that much of the food or supplement you take simply passes through your digestive system. With collagen peptides, you get a form of collagen that the body can make the most of it.

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And last but not least, since vitamin C is necessary for collagen synthesis, you need to provide enough of it with your diet to support the action of collagen supplements. For this reason, some products with hydrolyzed collagen contain vitamin C for optimal absorption.

Benefits-of-collagen-peptides

Benefits of collagen peptides  

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The two most commonly touted benefits of collagen peptides are improved skin health and reduced joint pain. But these products can also help support digestion and heart health, prevent bone loss and weight control.

Collagen-peptides-for-weight-loss

Collagen peptides for weight loss 

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Millions of people around the world have trouble maintaining or managing their weight. With commitments past work, kids, friends, and more, it can be difficult to fit weight loss or weight management into our busy days.

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The benefits of collagen peptides also include the potential to help you achieve your weight loss goals. In fact, liquid collagen for weight loss is one of the most popular ways that people provide themselves with collagen peptides.

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Evidence suggests that adding high-quality protein to your diet helps you feel full longer and can balance hunger hormones so you don't feel hungry as often. In addition, collagen can help you lose weight if combined with a healthy diet and regular physical activity. <a href="https://www.mdpi.com/1660-3397/17/3/157" target="_blank" data-ref="Effect of Oral Ingestion of Low-Molecular Collagen Peptides Derived from Skate (Raja Kenojei) Skin on Body Fat in Overweight Adults: A Randomized, Double-Blind, Placebo-Controlled Trial" rel="noopener">[ref.</a>&nbsp;3]&nbsp;

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Collagen peptides for muscle growth 

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In data cited from a study conducted in 2015, it was found that supplementing with protein in combination with endurance training can increase muscle mass and muscle strength in older individuals. More precisely, compared to placebo, supplementing with collagen peptides in combination with endurance training further improves body composition by increasing lean mass, muscle strength and fat loss. &nbsp;<a href="https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/collagen-peptide-supplementation-in-combination-with-resistance-training-improves-body-composition-and-increases-muscle-strength-in-elderly-sarcopenic-men-a-randomised-controlled-trial/9426E375742D094F91029FD0364815C4" target="_blank" data-ref="Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial | British Journal of Nutrition | Cambridge Core" rel="noopener">[ref. 4]</a>&nbsp;

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The daily dietary intake of hydrolyzed collagen appears to have another important potential role in improving bone remodeling at key stages of growth and development. These effects were described in a study conducted in 60 prepubertal Spanish children. &nbsp;<a href="https://www.degruyter.com/document/doi/10.1515/jpem.2011.009/html" target="_blank" data-ref="A nutritional intervention study with hydrolyzed collagen in pre-pubertal Spanish children: influence on bone modeling biomarkers" rel="noopener">[ref. 5]</a>&nbsp;

Collagen-Peptides-for-Hair-Growth

Collagen Peptides for Hair Growth 

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In a study that looked at the role of collagen peptides in increasing hair growth in women with thinned hair, there were also interesting results. The overall conclusion is that oral supplementation with collagen peptides safely and effectively promotes significant hair growth in women with temporary hair thinning. Other natural products, such as biotin, iron, and zinc, are also recommended for hair loss treatment. &nbsp;<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509882/#sec-2title" target="_blank" data-ref="Page not available - PMCTwitterFacebookLinkedInGitHubSM-TwitterSM-FacebookSM-Youtube" rel="noopener">[ref. 6]</a>&nbsp;

Collagen-Peptides-for-Skin-Health

Collagen Peptides for Skin Health 

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According to the study "The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials", oral intake of collagen peptides significantly increases skin hydration after 8 weeks of intake. The density of collagen in the dermis significantly increased and the fragmentation of the dermal collagen network significantly decreased after 4 weeks of supplementation. The effects persist for 12 weeks thereafter. &nbsp;<a href="https://onlinelibrary.wiley.com/doi/10.1111/jocd.12174" target="_blank" data-ref="Just a moment..." rel="noopener">[ref. 7]</a>&nbsp;

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Collagen is also an important tool for ensuring healthy hair and nails. Because of this, adding collagen to your diet as part of your anti-aging routine can be beneficial.&nbsp;

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The collagen content is concentrated in the dermis, the important middle layer of the skin that controls hair growth and blood flow. If you're wondering, "Does collagen help with hair loss?" the answer may be hidden in the dermis. This is important for another reason - by the middle of 20 years of life, we begin to lose about 1% of our collagen each year. One of the first signs of skin deterioration is sagging and wrinkles.

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A review of the dermatological benefits of collagen peptides found that oral collagen supplements can aid in wound healing and skin aging. Collagen has been found to help increase skin elasticity, hydration, and collagen density in the skin. <a href="https://pubmed.ncbi.nlm.nih.gov/30681787/" target="_blank" data-ref="Oral Collagen Supplementation: A Systematic Review of Dermatological Applications - PubMed" rel="noopener">[ref.</a>&nbsp;8]&nbsp;

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Also, increasing evidence demonstrates the efficacy of collagen peptides in improving skin physiology parameters in preclinical studies. Collagen peptides have been shown to increase hyaluronic acid production in dermal fibroblasts and improve skin barrier function by increasing the water content of the stratum corneum.

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Furthermore, collagen peptides induce collagen synthesis at the mRNA and protein level, as well as the production of stronger collagen fibrils,&nbsp; promote skin fibroblast growth and induce fibroblast migration. In contrast, clinical evidence on the efficacy of collagen peptides on human skin is still scarce. &nbsp;<a href="https://onlinelibrary.wiley.com/doi/10.1111/jocd.12174" target="_blank" data-ref="Just a moment..." rel="noopener">[ref. 9]</a>&nbsp;

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Another study looked at the effect of daily intake of collagen peptides on skin damage induced by repeated UV-B irradiation. The intake of collagen peptide (0.2 g/kg/day) suppressed the UV-B-induced decrease in skin hydration, epidermis hyperplasia and reduction of soluble collagen type I. These results suggest that collagen peptides are useful as a dietary supplement for suppressing UV-B-induced skin damage and photoaging. [ref.&nbsp;<a href="https://academic.oup.com/bbb/article/73/4/930/5947624" target="_blank" data-ref="Effects of Collagen Peptide Ingestion on UV-B-Induced Skin Damage" rel="noopener">10]</a>&nbsp;

Collagen-peptides-for-joint-health

Collagen peptides for joint health 

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The amino acids in collagen promote the growth of tissues, such as cartilage, and provide structural support to connective tissue. As we age, after intense exercise or after an injury, the cartilage in our joints can weaken. The benefits of collagen peptides include not only protection against joint damage and deterioration, but some evidence suggests that collagen may also prevent joint inflammation. &nbsp;<a href="https://www.tandfonline.com/action/cookieAbsent" target="_blank" data-ref="" rel="noopener">[ref. 11]</a>&nbsp;

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In a study in people with osteoarthritis, an undenatured type II collagen supplement (unchanged through the overheating process or the acidic process that many collagen producers use to convert collagen protein into collagen peptides) improved symptoms of knee osteoarthritis compared to placebo, and was well tolerated by patients. Further studies that elucidate the mechanism of action of this supplement are needed. &nbsp;<a href="https://nutritionj.biomedcentral.com/articles/10.1186/s12937-016-0130-8" target="_blank" data-ref="Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study - Nutrition Journal" rel="noopener">[ref. 12]</a>&nbsp;

Our bodies and minds need the right nutrients to work properly and recover quickly, and collagen peptides are some of the best supplements you can take to benefit your body. It is a special form of hydrolyzed collagen broken down into small easily digestible particles that can help with healthy skin, nails and hair, as well as relieve joint pain, muscle growth and weight management. Various studies have found that daily intake of collagen peptides for a certain period can help make your bones denser, slowing down the aging process, as well as skin hydration and elasticity, hair and nail growth.

Why collagen peptides are so effective, according to new scientific data

Why collagen peptides are so effective, according to new scientific results

Бетина Цветкова

What-is-rosacea

What is rosacea

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Rosacea is a common condition, affecting about 1-20% of the population. However, people often get the wrong diagnosis when they have rosacea, so the true frequency may be much higher.&nbsp;

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Rosacea, also called acne rosacea, is a non-contagious inflammation of the skin that affects the face exclusively. The small superficial blood vessels (capillaries) of the skin expand, creating the appearance of constant redness. Yellow pimples may appear on the forehead, cheeks and chin.&nbsp;

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Unlike acne, rosacea does not leave scars. The condition first appeared between the ages of 30 and 50. Frequent redness or blushing is usually the first sign. Over time, constant redness (erythema) may develop, as the capillaries enlarge and pustules begin to form. In men, severe rosacea can cause redness and enlargement of the nose.

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Symptoms of rosacea may include:

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<ul><li style="font-weight: 400;" aria-level="1">dilated capillaries&nbsp;</li><li style="font-weight: 400;" aria-level="1">constant redness of the nose and cheeks</li><li style="font-weight: 400;" aria-level="1">pimples on the forehead, cheeks and chin</li><li style="font-weight: 400;" aria-level="1">insensitive lumps under the skin</li><li style="font-weight: 400;" aria-level="1">slightly swollen cheeks and nose (hyperplasia)</li><li style="font-weight: 400;" aria-level="1">frequent redness</li><li style="font-weight: 400;" aria-level="1">burning or stinging sensation</li><li style="font-weight: 400;" aria-level="1">rash that is limited to the face area</li></ul>

What-home-remedies-for-rosacea-treatment-there-are

What home remedies for rosacea treatment there are

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Always consult a doctor about changes in your skin, even if they are minimal or on hidden parts of the body. While rosacea is usually relatively benign, skin changes may indicate a more serious underlying disease that needs medical treatment.

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In a diagnosed rosacea, it is usually recommended to administer topical and oral medications, as well as laser therapy to help reduce facial redness and inflammatory lesions.

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According to the individual condition and type of rosacea, a medical professional will recommend what exactly the treatment should be. In addition, home remedies can be used to treat rosacea if there are no contraindications.

Aloe-vera

Aloe vera

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The gel from the inner leaves of the aloe vera plant has a softening and moisturizing effect. It can be successfully applied as a topical remedy to relieve rosacea symptoms. &nbsp;<a href="https://www.ingentaconnect.com/content/fmc/scms/2011/00000030/00000003/art00004" target="_blank" data-ref="Botanicals and Anti-Inflammatories: Natural Ingredients for Rosac...: Ingenta Connect" rel="noopener">[ref. 1]</a>&nbsp;

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Many moisturizers contain aloe. You can use them and follow the directions on the packaging. You may be sensitive or allergic to aloe vera, so take a test before applying it to larger areas of the body. &nbsp;<a href="https://www.mdpi.com/1420-3049/25/9/2027" target="_blank" data-ref="Anti-Acne Action of Peptides Isolated from Burdock Root&mdash;Preliminary Studies and Pilot Testing" rel="noopener">[ref. 2]</a>&nbsp;

Burdock

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Burdock is a root plant that can also be found in the form of a supplement, extract or food. As an edible medicine, burdock root can purify the liver and clear skin diseases such as acne. Burdock extract can also be an effective remedy for rosacea.

Chamomile

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Like aloe vera, chamomile is common in products to hydrate and soften the skin. It is often used topically in herbal treatments for inflamed skin. &nbsp;<a href="https://www.dovepress.com/update-on-the-management-of-rosacea-peer-reviewed-fulltext-article-CCID" target="_blank" data-ref="Update on the management of rosacea | CCID" rel="noopener">[ref. 1]</a>&nbsp;

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Many studies support the action of chamomile as a successful medicine. Search moisturizing product containing natural chamomile, and use it by following the instructions on the label.

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Chamomile essential oil can also be diluted with base oil and applied to the skin. You can also make chamomile tea, wait for it to cool and use it to wash the skin or as a compress.

Black-oman

Black oman

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Omani is a plant that produces a compound called allantoin. This compound has the potential to relieve inflammatory skin reactions.

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A 2017 study on a product containing allantoin found that it improved symptoms with virtually no side effects. In addition, it reduces redness of the skin. Look for it in products such as creams, lotions or ointments and follow the directions on the label. &nbsp;<a href="https://www.researchgate.net/publication/320697152_An_Effective_yet_Gentle_Foaming_Facial_Cleanser_Specifically_Designed_for_Redness-Prone_Skin" target="_blank" data-ref="Just a moment..." rel="noopener">[ref. 4]</a>&nbsp;

Green-tea

Green tea

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Green tea is very rich in antioxidants and is available as a tea and herbal supplement. Research has shown that it can also be effective in dermatological conditions, including rosacea. &nbsp;<a href="http://europepmc.org/article/med/23346663" target="_blank" data-ref="Europe PMCEurope PMC" rel="noopener">[ref. 5]</a>&nbsp;

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Antioxidants are useful for inflammation, including skin diseases. In general, applying topical products with green tea is the best method of relieving rosacea, so we recommend this way.&nbsp;

If rosacea becomes acute and its symptoms become intolerable, some home remedies may help. However, they do not replace conservative treatment and therapy appointed by a doctor. Always before using herbal remedies, test the products on your hand in a small area to make sure you are not allergic. If you do not have a reaction within 24 hours, you can apply it to other parts of the body. A wide range of natural remedies, including chamomile, burdock, aloe vera, niacinamide and others, can help with rosacea.

hyperplasia

Why collagen peptides are so effective, according to new scientific data

Home Remedies for Rosacea You Should Try

Causes, conventional and herbal treatment of enlarged prostate