Rehmannia is a genus of six species of flowering plants in the order Lamiales and family Orobanchaceae, endemic to China. It is the only member of the monotypic tribe Rehmannieae. Contrary to the immense majority of the taxa of Orobanchaceae, Rehmannia is not parasitic.

Rehmannia is named for Joseph Rehmann (1788–1831), a physician in St. Petersburg.

The name 'Rehmannia' has also been given to a genus of Jurassic ammonites of the family Reineckeidae.

The genus was included in the family Scrophulariaceae ...

rehmannia

_-1_0

Author: Rositsa Tashkova, Master of Molecular Biology and Microbiology

_-1_1

_-1_2

Osteoporosis is a disease that mainly affects women after menopause. Unfortunately, only then do we start thinking about it, and measures can be taken much earlier. For example, active sports at a young age is a factor that is often overlooked, but in fact has a strong positive effect on bone density and therefore their strength later in life.

Role-of-herbs-in-the-treatment-and-prevention-of-osteoporosis

Role of herbs in the treatment and prevention of osteoporosis

Role-of-herbs-in-the-treatment-and-prevention-of-osteoporosis_0_0

Studies are also being carried out on various herbs and medicinal plants that can be used to increase bone density and combat osteoporosis. They may serve as a complementary medicine to the main treatment, especially in postmenopausal women.

Role-of-herbs-in-the-treatment-and-prevention-of-osteoporosis_0_1

Some of these plants have estrogen-like properties that are important for bone health. It is good to keep in mind that herbal treatments are supportive and have a slow effect, and therefore it is recommended to use them for prevention and maintenance, and not as a single treatment.

Role-of-herbs-in-the-treatment-and-prevention-of-osteoporosis_0_2

Herbs can exert an impact on inflammatory processes and metabolism, reduce bone destruction and help preserve calcium in the body.

Role-of-herbs-in-the-treatment-and-prevention-of-osteoporosis_0_3

Eleuthero-(Acanthopanax-senticosus)

Eleuthero (Acanthopanax senticosus)

Eleuthero-(Acanthopanax-senticosus)_1_0

The herb is also called &nbsp;devil's bush, Siberian ginseng, ciwujia, Devil's shrub, shigoka, touch-me-not, wild pepper, or kan jang. A study by Hwang et al. has found that taking 3 grams of powdered extract of the herb per day for 6 months leads to positive effects on bone structure in menopausal women. [<a href="https://www.bioseek.eu/en/eng/research/pubmed/The_effects_of_Acanthopanax_senticosus_extract_on_bone_turnover_and_bone_mineral_density_in_Korean_postmenopausal_women_19452124" target="_blank" rel="noopener">ref.1</a>]

Red-clover-(Trifolium-pratense)-contains-estrogen-like-compounds

Red clover (Trifolium pratense) contains estrogen-like compounds

Red-clover-(Trifolium-pratense)-contains-estrogen-like-compounds_2_0

It is believed that red clover contains estrogen-like compounds, which may be due to its potential positive effect on bone density observed in some studies. [<a href="https://www.hindawi.com/journals/ecam/2015/689138/" target="_blank" rel="noopener">ref.2</a>]

Red-clover-(Trifolium-pratense)-contains-estrogen-like-compounds_2_1

Unfortunately, these estrogen-like compounds may interact adversely with other medications, as well as not be suitable for some patients suffering or prone to other diseases (for example, estrogen-dependent breast cancer) therefore a preliminary consultation with a doctor is necessary.

Red-clover-(Trifolium-pratense)-contains-estrogen-like-compounds_2_2

Soybeans-(Glycine-max)-may-have-a-protective-effect-on-bones

Soybeans (Glycine max) may have a protective effect on bones

Soybeans-(Glycine-max)-may-have-a-protective-effect-on-bones_3_0

Soybeans contain isoflavons - they also resemble estrogen, and it is believed that for this reason they can have a protective effect on bones against loss of density.

Soybeans-(Glycine-max)-may-have-a-protective-effect-on-bones_3_1

Many different studies have found such an effect of taking soy isoflavons. But here is also the same warning about the likelihood of interaction and adverse effects in some patients. [<a href="https://www.bioseek.eu/en/eng/research/pubmed/The_pros_and_cons_of_phytoestrogens_20347861" target="_blank" rel="noopener">ref.3</a>]

Genistein

Genistein_4_0

Phytoestrogen genistein also belongs to the group of isoflavons and has an oestrogen-like effect. For the first time, the substance is isolated from the plant dyer's greenweed or dyer's broom&nbsp;(Genista tinctoria), from whose Latin name comes the name of the substance.

Genistein_4_1

Genistein is also found in soybeans (Glycine max), lupine (Lupinus), broad beans or fava bean (Vicia faba), Psoralea, kudzu (Japanese arrowroot or Chinese arrowroot), coffee.

Genistein_4_2

Various studies [<a href="https://www.bioseek.eu/en/eng/research/pubmed/Effects_of_genistein_and_hormone_replacement_therapy_on_bone_loss_in_early_postmenopausal_women_a_randomized_double_blind_placebo_controlled_study_12369794" target="_blank" rel="noopener">ref.4</a>] establish the effectiveness of this phytoestrogen in osteoporosis, and the mechanisms and contraindications are similar to those described above.

Genistein_4_3

Chinese-traditional-medicine-and-herbal-combinations

Chinese traditional medicine and herbal combinations

Chinese-traditional-medicine-and-herbal-combinations_5_0

A number of herbal combinations of Chinese traditional medicine have shown effectiveness against osteoporosis. [<a href="http://j.skums.ac.ir/Article/jskums-90" target="_blank" rel="noopener">ref.5</a>] Here we will focus on some of them:

Chinese-traditional-medicine-and-herbal-combinations_5_1

<ul>
<li style="font-weight: 400;" aria-level="1">Yang Huo San Zi Tang - contains seeds of white mustard (Sinapis alba), shiso seeds (Perilla frutescens), daikon turnip seeds (Raphanus sativus var. Longipinnatus);</li>
<li style="font-weight: 400;" aria-level="1">Yigu of capsules - contains common wheat (Triticum aestivum), dried fruits of Psoralea corylifolia, sweet wormwood (Artemisia annua), Xanthium sibiricum, bitter apricot nuts, ricebean (Vigna umbellata).</li>
<li style="font-weight: 400;" aria-level="1">Bo-gu Ling;</li>
<li style="font-weight: 400;" aria-level="1">Classic Yin and Yang Tonic Formula - contains a variety of phytoestrogens, such as isoflavones, lignans and coumarin;</li>
<li style="font-weight: 400;" aria-level="1">Xian Ling GuBao - consists of 9 herbs, among which Еpimedium, psoralen, Rehmannia root, danshen or also known as red sage (Salvia miltiorrhiza), Anemarrhena asphodeloides&nbsp;and others.</li>
</ul>

Chinese-traditional-medicine-and-herbal-combinations_5_2

Some herbs and herbal combinations have a positive effect on osteoporosis, especially in menopausal women. However, due to the similarity of the active substances in these medicinal plants with the hormone estrogen, which are due to their effects, it is necessary to carefully monitor the therapy and the approach to each patient should be individual, according to their medical history, diseases and medications they use.