Thrombocytopenia is a condition characterized by abnormally low levels of platelets, also known as thrombocytes, in the blood.A normal human platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. Values outside this range do not necessarily indicate disease. One common definition of thrombocytopenia requiring emergency treatment is a platelet count below 50,000 per microliter. Thrombocytopenia can be contrasted with thrombocythemia, and thrombocytosis, conditions of an abnormally ...

thrombocytopenia

_-1_0

Symptoms-of-high-aPTT

Symptoms of high aPTT

Symptoms-of-high-aPTT_0_0

<ul><li style="font-weight: 400;" aria-level="1">Easy bruising</li><li style="font-weight: 400;" aria-level="1">Excessive bleeding</li><li style="font-weight: 400;" aria-level="1">Blood in urine or stools</li><li style="font-weight: 400;" aria-level="1">Prolonged menstrual bleeding</li><li style="font-weight: 400;" aria-level="1">Blood clots in legs or lungs</li></ul>

Possible-causes-of-high-aPTT

Possible causes of high aPTT

Possible-causes-of-high-aPTT_1_0

<ul><li style="font-weight: 400;" aria-level="1">Hemophilia (a genetic disorder that affects blood clotting)</li><li style="font-weight: 400;" aria-level="1">Liver disease</li><li style="font-weight: 400;" aria-level="1">Lupus (a chronic autoimmune disease)</li><li style="font-weight: 400;" aria-level="1">Von Willebrand disease (a genetic bleeding disorder)</li><li style="font-weight: 400;" aria-level="1">Heparin (a blood thinner) or Warfarin (a medication used to prevent blood clots) use</li></ul>

Possible-side-effects-of-medicines-that-may-cause-high-aPTT

Possible side effects of medicines that may cause high aPTT

Possible-side-effects-of-medicines-that-may-cause-high-aPTT_2_0

<ul><li style="font-weight: 400;" aria-level="1">Heparin-induced thrombocytopenia (HIT) caused by heparin use</li><li style="font-weight: 400;" aria-level="1">Overdose of Warfarin</li></ul>

Possible-side-effects-of-medicines-that-may-cause-high-aPTT_2_1

Herbal-and-natural-remedies

Herbal and natural remedies

Herbal-and-natural-remedies_3_0

<ul><li style="font-weight: 400;" aria-level="1">Garlic (Allium sativum): Garlic has blood-thinning properties that can help lower aPTT levels.</li><li style="font-weight: 400;" aria-level="1">Ginger (Zingiber officinale): Ginger contains compounds that can help prevent blood clots.</li><li style="font-weight: 400;" aria-level="1">Ginkgo (Ginkgo biloba): Ginkgo has been found to improve blood flow and reduce the risk of blood clots.</li></ul>

Suggestions-to-change-bad-living-habits-that-can-cause-high-aPTT

Suggestions to change bad living habits that can cause high aPTT

Suggestions-to-change-bad-living-habits-that-can-cause-high-aPTT_4_0

<ul><li style="font-weight: 400;" aria-level="1">Avoid smoking</li><li style="font-weight: 400;" aria-level="1">Maintain a healthy weight</li><li style="font-weight: 400;" aria-level="1">Exercise regularly</li><li style="font-weight: 400;" aria-level="1">Eat a healthy diet rich in fruits, vegetables, and whole grains</li></ul>

Suggestions-to-change-bad-living-habits-that-can-cause-high-aPTT_4_1

Questions-and-Answers

Questions and Answers

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:

Below are ten frequently asked questions that are not covered in the article:

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_0

Q: Can high aPTT be inherited?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_1

A: Yes, some genetic disorders such as hemophilia and von Willebrand disease can cause high aPTT.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_2

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_3

Q: Is high aPTT dangerous?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_4

A: High aPTT can be a sign of a serious medical condition such as a bleeding disorder or clotting disorder, which can be life-threatening if left untreated.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_5

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_6

Q: Can stress cause high aPTT?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_7

A: Stress itself does not cause high aPTT, but stress can cause an increase in adrenaline and other hormones that can affect blood clotting.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_8

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_9

Q: How is high aPTT treated?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_10

A: The treatment for high aPTT depends on the underlying cause. This can range from medication to lifestyle changes to surgery in some cases.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_11

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_12

Q: Can high aPTT affect pregnancy?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_13

A: Yes, high aPTT can increase the risk of miscarriage, stillbirth, or premature delivery in pregnant women.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_14

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_15

Q: Can herbal supplements interfere with medical treatments for high aPTT?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_16

A: Yes, some herbal supplements can interfere with blood thinners and other medications used to treat high aPTT. It is important to talk to your doctor before taking any herbal supplements.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_17

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_18

Q: Can high aPTT cause infertility?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_19

A: High aPTT itself is not a direct cause of infertility, but underlying medical conditions that cause high aPTT can affect fertility.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_20

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_21

Q: Can high aPTT be caused by vitamin deficiencies?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_22

A: Yes, low levels of vitamin K or vitamin C can affect blood clotting and lead to high aPTT.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_23

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_24

Q: How often should a person with high aPTT have their blood checked?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_25

A: The frequency of blood tests depends on the underlying cause and severity of high aPTT. Your doctor will determine how often you should have your blood checked.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_26

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_27

Q: Can exercise worsen high aPTT?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_28

A: Exercise itself does not worsen high aPTT, but certain high-impact activities may increase the risk of injury and bleeding in people with high aPTT. It is important to talk to your doctor before starting any new exercise program.

In summary, high aPTT can be caused by several medical conditions, medications, and lifestyle factors. If you experience any symptoms of high aPTT, it is essential to consult with a hematologist, a specialist in blood disorders. Herbal and natural treatments can be used in conjunction with medical treatments, but it is important to discuss them with your doctor first. Making lifestyle changes such as quitting smoking, maintaining a healthy weight, exercising regularly, and eating a healthy diet can also help manage high aPTT. By understanding the causes and management strategies of high aPTT, you can take control of your health and prevent complications.

High aPTT: Understanding the Causes and Management Strategies

https://sanatio.s3.eu-west-1.amazonaws.com/c619a99b-013b-48f6-bcb5-2f99f1e7e6ea_middle.jpg

Екипът на Санацио

Photo by christopher lemercier on Unsplash

Symptoms-of-low-platelet-count

Symptoms of low platelet count

Autoimmune-diseases:

1. Autoimmune diseases:

Autoimmune-diseases:_0_0

<ul><li style="font-weight: 400;" aria-level="2">Immune thrombocytopenia (ITP): An autoimmune disorder where the body attacks its own platelets, leading to low platelet count. Symptoms include easy bruising, bleeding gums, and petechiae.</li><li style="font-weight: 400;" aria-level="2">Lupus: A chronic autoimmune disease that can cause inflammation in various organs and body tissues, including platelets, resulting in thrombocytopenia.</li><li>Rheumatoid arthritis: A long-term autoimmune disorder that primarily affects the joints but can also impact platelet count.</li><li style="font-weight: 400;" aria-level="2">Consult a rheumatologist or hematologist for these conditions.</li></ul>

Infections:

2. Infections:

Infections:_0_0

<ul><li style="font-weight: 400;" aria-level="2">Hepatitis C: A viral infection that affects the liver and can cause thrombocytopenia by disrupting platelet production or increasing platelet destruction.</li><li style="font-weight: 400;" aria-level="2">HIV: The virus that causes AIDS can lead to thrombocytopenia by impairing platelet production or increasing platelet destruction.</li><li>Pylori infection: A bacterial infection in the stomach that has been linked to an increased risk of immune thrombocytopenia.</li><li style="font-weight: 400;" aria-level="2">Consult an infectious disease specialist or gastroenterologist.</li></ul>

Bone-marrow-disorders:

3. Bone marrow disorders:

Bone-marrow-disorders:_0_0

<ul><li style="font-weight: 400;" aria-level="2">Leukemia: A cancer of the blood-forming tissues, including bone marrow, that can lead to thrombocytopenia by crowding out healthy platelet-producing cells.</li><li style="font-weight: 400;" aria-level="2">Myelodysplastic syndromes: A group of disorders characterized by abnormal bone marrow cell production, which can cause a decline in platelet count.</li><li>Aplastic anemia: A rare condition in which the bone marrow fails to produce enough blood cells, including platelets.</li><li style="font-weight: 400;" aria-level="2">Consult a hematologist or oncologist.</li></ul>

Genetic-conditions:

4. Genetic conditions:

Genetic-conditions:_0_0

<ul><li style="font-weight: 400;" aria-level="2">Wiskott-Aldrich syndrome: A rare genetic disorder that affects the immune system and leads to low platelet count, making bleeding and bruising more likely.</li><li>May-Hegglin anomaly: A rare genetic condition characterized by abnormally large platelets and a reduced platelet count.</li><li style="font-weight: 400;" aria-level="2">Consult a genetic counselor or hematologist.</li></ul>

Drug-induced-thrombocytopenia

Drug-induced thrombocytopenia

Drug-induced-thrombocytopenia_1_0

<ul><li style="font-weight: 400;" aria-level="1">Heparin</li><li style="font-weight: 400;" aria-level="1">Quinine</li><li style="font-weight: 400;" aria-level="1">Nonsteroidal anti-inflammatory drugs (NSAIDs)</li><li style="font-weight: 400;" aria-level="1">Sulfonamides</li><li style="font-weight: 400;" aria-level="1">Chemotherapy medications</li></ul>

Drug-induced-thrombocytopenia_1_1

Papaya-leaf-extract-(Carica-papaya)

Papaya leaf extract (Carica papaya)

Papaya-leaf-extract-(Carica-papaya)_2_0

Studies suggest that papaya leaf extract can help increase platelet count in individuals with dengue fever, and it may have potential benefits for those with thrombocytopenia.

Ashwagandha-(Withania-somnifera)

Ashwagandha (Withania somnifera)

Ashwagandha-(Withania-somnifera)_2_0

This adaptogenic herb is known for its immune-boosting and stress-reducing properties, which may be beneficial for individuals with thrombocytopenia caused by autoimmune diseases or stress-related factors.

Milk-thistle-(Silybum-marianum)

Milk thistle (Silybum marianum)

Milk-thistle-(Silybum-marianum)_2_0

Milk thistle has been shown to support liver health, which may help improve platelet count in cases where thrombocytopenia is related to liver disorders.

Astragalus-membranaceus

Astragalus membranaceus

Astragalus-membranaceus_2_0

Known for its immune-enhancing properties, astragalus may help support platelet production and reduce the risk of infections that can cause thrombocytopenia.

Turmeric-(Curcuma-longa)

Turmeric (Curcuma longa)

Turmeric-(Curcuma-longa)_2_0

Turmeric's active compound, curcumin, has anti-inflammatory and antioxidant properties, which may help improve platelet count in individuals with thrombocytopenia due to inflammation or oxidative stress.

Turmeric-(Curcuma-longa)_2_1

Lifestyle-changes:

Lifestyle changes:

Lifestyle-changes:_3_0

<ul><li style="font-weight: 400;" aria-level="1">Limit alcohol consumption</li><li style="font-weight: 400;" aria-level="1">Maintain a healthy diet rich in vitamins and minerals</li><li style="font-weight: 400;" aria-level="1">Practice good hygiene to reduce the risk of infections</li><li style="font-weight: 400;" aria-level="1">Exercise regularly to improve overall health</li></ul>

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:

Here are the answers to 10 frequently asked questions that are not addressed in the article:

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_0

Q: How is thrombocytopenia diagnosed?

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_1

A: Thrombocytopenia is diagnosed through blood tests, including a complete blood count (CBC).

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_2

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_3

Q: Can pregnancy cause thrombocytopenia?

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_4

A: Yes, gestational thrombocytopenia can occur during pregnancy but usually resolves after delivery.

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_5

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_6

Q: Is thrombocytopenia a lifelong condition?

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_7

A: It depends on the underlying cause; some cases may be temporary, while others may require long-term management.

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_8

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_9

Q: Can I exercise with thrombocytopenia?

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_10

A: Consult your doctor before starting any exercise regimen, but generally, low-impact exercises are recommended.

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_11

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_12

Q: Is thrombocytopenia contagious?

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_13

A: No, thrombocytopenia itself is not contagious, but some infections that cause it can be transmitted.

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_14

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_15

Q: Can thrombocytopenia be genetic?

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_16

A: Yes, some genetic conditions can lead to thrombocytopenia.

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_17

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_18

Q: Can certain foods help increase platelet count?

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_19

A: Foods rich in vitamins B12, C, K, and folate can help support platelet production, such as leafy greens, citrus fruits, and lean meats.

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_20

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_21

Q: Can stress affect platelet count?

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_22

A: Chronic stress may indirectly impact platelet count by affecting the immune system or exacerbating underlying conditions.

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_23

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_24

Q: Is thrombocytopenia common in children?

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_25

A: Thrombocytopenia can occur in children, but the most common cause, immune thrombocytopenia, is usually temporary and resolves on its own.

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_26

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_27

Q: Can thrombocytopenia cause anemia?

Here-are-the-answers-to-10-frequently-asked-questions-that-are-not-addressed-in-the-article:_4_28

A: Thrombocytopenia and anemia are separate conditions, but they can coexist or share common underlying causes such as bone marrow disorders or certain medications.

Thrombocytopenia, or low platelet count, can result from various diseases, conditions, and medications. By understanding the symptoms and causes, you can take steps to manage this condition. Consult the appropriate medical professionals, consider herbal and natural treatments, and make healthy lifestyle choices to improve your platelet count and overall well-being.

Low Platelet Count: Understanding Thrombocytopenia

https://sanatio.s3.eu-west-1.amazonaws.com/db3db1bc-4372-495b-aebd-20a9d599fff4_middle.jpg

Author: Rositsa Tashkova, Master of Molecular Biology and Microbiology

_-1_1

_-1_2

Cancer is extremely prevalent and is one of the leading causes of death in the world. The most common treatments are chemotherapy and radiation therapy. But unfortunately, they have many and severe side effects that worsen, albeit temporarily, the quality of life of patients and are a major reason for refusing treatment.

_-1_3

Fortunately, some natural products can alleviate the side effects induced by chemotherapy and radiation therapy:

_-1_4

<ul>
<li style="font-weight: 400;" aria-level="1">oral mucositis (inflammation and mouth ulcers),</li>
<li style="font-weight: 400;" aria-level="1">gastrointestinal toxicity (nausea, vomiting),</li>
<li style="font-weight: 400;" aria-level="1">hepatotoxicity (liver),</li>
<li style="font-weight: 400;" aria-level="1">nephrotoxicity (kidneys),</li>
<li style="font-weight: 400;" aria-level="1">damage to the hematopoietic system (blood formation),</li>
<li style="font-weight: 400;" aria-level="1">cardiotoxicity (heart),</li>
<li style="font-weight: 400;" aria-level="1">neurotoxicity (nervous system).</li>
</ul>

_-1_5

In this article, you will find information on the topic based on research. We hope it will be useful for you or your relatives and acquaintances suffering from oncological disease.

_-1_6

Mechanisms-behind-herbs-ability-to-suppress-side-effects

Mechanisms behind herbs ability to suppress side effects

Mechanisms-behind-herbs-ability-to-suppress-side-effects_0_0

Natural products, including raw extracts enriched with bioactive components and pure compounds derived from herbs, as well as herbal formulas, can effectively reduce the strength of chemotherapy and radiation therapy induced side effects mainly due to their antioxidant and anti-inflammatory actions.

Mechanisms-behind-herbs-ability-to-suppress-side-effects_0_1

In addition, certain natural products are able to [<a href="https://www.bioseek.eu/en/eng/research/pubmed/Natural_Product_Interventions_for_Chemotherapy_and_Radiotherapy_Induced_Side_Effects_30459615#B109" target="_blank" rel="noopener">ref.1</a>]:

thrombocytopenia

Low Platelet Count: Understanding Thrombocytopenia

Herbs that relieve chemotherapy and radiation therapy adverse side effects